Fig. 5
From: Multifunctional silica nanocomposites prime tumoricidal immunity for efficient cancer immunotherapy
Antitumor effect of DMSN-PEI@125a in vivo. The TC-1 tumor models (n = 5) were i.t. injected with ddH2O, DMSN-PEI@NC, DMSN-PEI@125a, and miR-125a every 2 days for six times from day 8 after tumor inoculation. A Tumor growth curves of different treatments. Arrows: the day of administration. B Photographic images of representative tumors on day 20 after tumor implantation. C, D mRNA expression levels of C apoptosis-related genes (caspase-3, caspase-9, STAT-3) and D damage-associated molecular patterns (HMGB-1, CRT) in tumors