Fig. 1
From: Fenton/Fenton-like metal-based nanomaterials combine with oxidase for synergistic tumor therapy
Reproduced with permission from Ref [28], copyright © 2016 Wiley–VCH. B1 Schematic diagram of tumor therapeutic performance of biodegradable rFeOx-HMSN nanoparticles. B2 (a) Body weight changes of 4T1 bearing mice after different treatments. Relative tumor volumes of 4T1-bearing mice administrated with varied doses of PEG/rFeOx-HMSN nanocatalyst (b) intratumorally and (c) intravenously. Digital photographs of dissected tumors after the therapeutic process from (d) intratumoral and (e) intravenous groups. Reproduced with permission from Ref [29], copyright © 2018 Elsevier. C1 Schematic of CuS-Fe boosting transformation of Fe (III) into Fe (II) for highly improving CDT. C2 GSH level in HeLa cells after difffferent treatments; Cell viability in HeLa cells and NIH3T3 cells after different treatments. C3 Changes in body weight of mice and tumor volume during different treatments. Reproduced with permission from Ref [30], copyright © 2019 American Chemical Society
Iron-mediated Fenton reaction triggers CDT. A1 Preparation of AFeNPs. A2 The optimal value for AFeNPs catalyzed hydrogen peroxide decomposition was pH = 5.4. A3 Changes in relative volume of tumors after different treatments.