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Fig. 10 | Journal of Nanobiotechnology

Fig. 10

From: Fenton/Fenton-like metal-based nanomaterials combine with oxidase for synergistic tumor therapy

Fig. 10

Reproduced with permission from Ref [48], copyright © 2018 Elsevier. B1 Schematic diagram showing the fabrication of HGTFT nanoreactors and their applications for starvation therapy, CDT, and chemotherapy. B2 Tumor growth inhibition rates of different formulations. And apoptosis/necrosis rates determined by the TUNEL assay. B3 Tumor growth profiles of the mice in the different groups. Reproduced with permission from Ref [107], copyright © 2020 WILEY–VCH

"Metal-oxidase" system combined with hypoxia activation therapy synergistic anti-tumor system. A1 Scheme illustrating the design of combining starvation and hypoxia-activated therapy by co-delivery of liposome-GOx and liposome-AQ4N into tumors. A2 Relative viabilities of 4T1 cells after 24 h incubated with different concentrations of glucose and liposome-GOx. And relative viabilities of 4T1 cells after 48 h incubation with different concentrations of liposome-AQ4N under the normoxia or hypoxia culture condition. A3 Tumor growth curves of mice after various different treatments indicated.

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