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Fig. 8 | Journal of Nanobiotechnology

Fig. 8

From: Fenton/Fenton-like metal-based nanomaterials combine with oxidase for synergistic tumor therapy

Fig. 8

Reproduced with permission from Ref [91], copyright © 2020, American Chemical Society. B1 Schematic illustration for the functioning mechanism of M@AAO@HFe–TA nanocapsules. B2 Protein expression of Bcl-2/Bax/Cyt C/caspase 3 mitochondrial apoptotic pathway in 4T1 cells under different treatments. And schematic illustration of in vitro antitumor mechanism of M@AAO@HFe–TA nanocapsules. B3 Body weight and tumor volume in different mice groups during the 14 days of treatment. Reproduced with permission from Ref [94], copyright © 2020, Royal Society of Chemistry

The synergistic anti-tumor effect of " iron-LOX " and "iron-AAO". A1 The tandem biological–chemical catalytic reactions for effective catalytic tumor treatment based on the characteristic of TME. A2 Cell rescue profiles of 4T1 cells’ cytotoxicity induced by LFZ NPs (10 μg/mL) with different concentrations of l-ascorbic acid. A3 The relative tumor volume and the body weight under different treatments.

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