Fig. 5
Photothermal effective and accumulative DOX release of FA-MSNR/LMDI@MP/MPCM. A Temperature change curves and infrared thermal images of FA-MSNR/LMDI@MP/MPCM with NIR irradiation. B Temperature change curves and infrared thermal images of tumor-bearing nude mice after intravenous injection of FA-MSNR/LMDI@MP/MPCM with NIR irradiation. C Accumulative Dox release curves of FA-MSNR/LMDI@MP/MPCM containing 400 μg mL−1 ICG at 37 °C, pH 7.4 or pH 6.5, with or without NIR irradiation for 10 min. D Accumulative Dox release curves of FA-MSNR/LMDI@MP/MPCM containing 400 μg mL−1 ICG within 12 h at 37 °C, pH 7.4 or pH 6.5. E Cumulative DOX release from FA-MSNR/LMDI@MP/MPCM in response to NIR irradiation on/off cycle. F LSCM images of 4T1 cells incubated with FA-MSNR/LMDI@MP/MPCM before and after NIR irradiation. (The arrow showed the nucleus) Green: DOX