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Fig. 1 | Journal of Nanobiotechnology

Fig. 1

From: Chitosan oligosaccharides packaged into rat adipose mesenchymal stem cells-derived extracellular vesicles facilitating cartilage injury repair and alleviating osteoarthritis

Fig. 1

Characterization of extracellular vesicles (EVs) isolated from rat adipose mesenchymal stem cells (AMSCs), and EVs-chitosan oligosaccharide (COS) conjugates (EVs-COS). A The morphology of rat AMSCs-derived EVs observed by transmission electron microscopy (TEM). B The particle size distribution of EVs determined by a Nanosight NS300 particle size analyzer (NTA). C The expressions of EVs surface markers (CD63, TSG101, and CD9) measured using Western blot. D The morphology of EVs-COS by using TEM. E The particle size distribution of EVs-COS measured by NTA. F EVs and EVs-COS taken up by rat chondrocytes visualized using PKH67 staining kit (green fluorescence)

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