Fig. 2

Physiological functions of neutrophils and PLD@NEs under different conditions. a Superoxide generation after stimulation with fMLP for 0.5 h. n = 3. b Changes in CD11b expression on the membranes of neutrophils after treatment with different concentrations of fMLP for 0.5 h. n = 3. c Chemotactic activity after treatment with different concentrations of fMLP for 0.5 h. n = 3. d Cellular uptake of PLD by neutrophils (n = 3) and color changes of neutrophils before and after PLD loading. e Determination of the amounts of PLD retained in PLD@NEs under the absence of fMLP/PMA, the presence of fMLP (100 nM), or the presence of PMA (100 nM). n = 3