Skip to main content
Fig. 2 | Journal of Nanobiotechnology

Fig. 2

From: In vivo performance of electrospun tubular hyaluronic acid/collagen nanofibrous scaffolds for vascular reconstruction in the rabbit model

Fig. 2

Cell adherence and resistance to platelet adherence assessments. H&E staining of the cross-section of a tubular HA/collagen nanofibrous scaffold before (a) and after (b) cell seeding, and a rabbit native carotid artery (c). Vascular ECs and SMCs adhere to the lumen and exterior, respectively, of the tubular HA/collagen nanofibrous scaffold after 7 days cell seeding. A thin layer of flat ECs (red arrows) lining the lumen, bundles of filaments with dense bodies (black arrows) are characteristic of SMCs. Scale bars, 20 μm. SEM micrographs of HA/collagen scaffold without (d) and lined with vascular ECs (e) after exposure to blood for 15 min. Yellow arrows show the morphology of rabbit platelets. Scale bars, 4 μm. f Quantification of platelet activation by measuring the expression of sP-selectin release in rabbit PRP following incubation with HA/collagen scaffold without and lined with vascular ECs (n = 4). **p\(<\) 0.01

Back to article page