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Fig. 2 | Journal of Nanobiotechnology

Fig. 2

From: Gene augmented nuclear-targeting sonodynamic therapy via Nrf2 pathway-based redox balance adjustment boosts peptide-based anti-PD-L1 therapy on colorectal cancer

Fig. 2

A Confocal images, B flow cytometry curves and C quantitative analysis of CT26 cells after 4 h incubation with FITC-Nrf2-siRNA, IR780, TIR and TIR@FITC-Nrf2-siRNA. D Confocal images of CT26 tumor spheroids after 4 and 12 h incubation with IR780, TIR and TIR@siRNA. E Confocal images of CT26 cells after 2 and 4 h incubation with TIR@siRNA while the nuclei stained with DAPI and lysosome stained with lysotracker red. F The fluorescence colocalization curves of red and green fluorescence at 2 h (upper) and 4 h (downer). *P < 0.05 and **P < 0.01 for the comparisons between two treatment groups

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