Fig. 5
From: Nanomedicine for increasing the oral bioavailability of cancer treatments
Gut-on-a-chip general schematic. A typical gut-on-a-chip (GoC) is composed of two chambers separated by a semipermeable membrane. One chamber is seeded with cells reconstituting the GIT epithelium, while the second is seeded with other cell phenotypes representing the sub-epithelial environment. (Reprinted from Ashammakhi, N., Nasiri, R., De Barros, N. R., Tebon, P., Thakor, J., Goudie, M., Shamloo, A., Martin, M. G., Khademhosseni, A. 2020. Gut-on-a-chip: Current progress and future opportunities. Biomaterials 225:120,196. Elsevier.)