Fig. 6
From: Nanomedicine for increasing the oral bioavailability of cancer treatments
Properties of chitosan in oral nanomedicine. A Electrostatic forces between positively charged chitosan nanoparticles and negatively charged GIT epithelial cell surface favor their interaction and eventually lead to tight junction change of conformation that increases transcellular diffusion of particles and their payload. B Chitosan properties in generating nanoparticles for oral drug delivery. A reprinted from Hong S-C, Yoo S-Y, Kim H, Lee J. 2017. Chitosan-based multifunctional platforms for local delivery of therapeutics. Marine Drugs 15(3):60. MDPI)