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Fig. 7 | Journal of Nanobiotechnology

Fig. 7

From: Chemo-photodynamic therapy with light-triggered disassembly of theranostic nanoplatform in combination with checkpoint blockade for immunotherapy of hepatocellular carcinoma

Fig. 7

Lysosome disruption, mitochondrial membrane potential depolarization, cytochrome-c release, as well as caspase-3 activation, following TB@RTK micelle-mediated PDT in Hep 1–6 cells. A Lysosome disruption was assessed by LysoTracker Green staining after different treatments. In PDT group, the fluorescent intensity decreased. Scale bar: 50 μm. B Mitochondrial membrane potential (ΔΨm) in Hep 1–6 cells after the indicated treatments. Scale bar: 20 μm. C Immunofluorescence co-staining of cytochrome-c and Tom20. Tom20 indicates the mitochondria. Scale bar: 10 μm. D Caspase-3 activation in Hep 1–6 cells after different treatments

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Journal of Nanobiotechnology

ISSN: 1477-3155

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