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Fig. 9 | Journal of Nanobiotechnology

Fig. 9

From: Chemo-photodynamic therapy with light-triggered disassembly of theranostic nanoplatform in combination with checkpoint blockade for immunotherapy of hepatocellular carcinoma

Fig. 9

Toxicity of TB/PTX@RTK micelles in vivo. A Body weight changes of C57BL/6 mice after injection of saline (negative control), free PTX, and TB/PTX@RTK micelles, respectively. Data represent mean ± SD (n = 3). B H&E staining images of various organ slices from C57BL/6 mice 7 days after the indicated treatments. Scale bar: 50 μm. C Red blood cells (RBC), red blood cell distribution width (RDW), hematocrit (HCT), mean corpuscular volume (MCV), mean corpuscular hemoglobin concentration (MCHC), hemoglobin (HGB), wight blood cells (WBC), neutrophils (NE), platelet (PLT), and platelet distribution width (PDW) levels in C57BL/6 mice of different groups. D The serum levels of CK-MB, ALT, AST, BUN, and Cre in C57BL/6 mice of different groups

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