Fig. 5

In vitro study of the light-triggered drug release performance and cytotoxicity. a CLSM images of 4T1 cells incubated with NR/Pt/BTNPs with or without light irradiation. Scale bar: 20 µm. b Cell viability of HUVECs treated with Pt/BTNPs with or without light irradiation (n = 5). c Cell viability of 4T1 cells treated with PTX/Pt/BTNPs with or without light irradiation (n = 5). d CLSM images showing the actin change of 4T1 cells. Cells were treated for 4 h and incubated in fresh cell culture media for another 24 h. Scale bar: 20 µm. All irradiations were done with a 635 nm laser (50 mW/cm², 10 min)