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Fig. 6 | Journal of Nanobiotechnology

Fig. 6

From: Self-assembled nanoparticles containing photosensitizer and polycationic brush for synergistic photothermal and photodynamic therapy against periodontitis

Fig. 6

PTT and PDT performances of sPDMA@ICG NPs in periodontitis rats. a Photos of periodontitis rat with administration of sPDMA@ICG NPs and laser irradiation. b Confocal microscopic images of DCFH-DA stained tissue sections sourced from periodontitis lesions in the rats after treatments of sPDMA, ICG and sPDMA@ICG NPs with or without laser irradiation. c Comparison for the mean fluorescence intensities of produced DCF in periodontal tissues. Infrared thermal images of periodontal tissues during laser irradiation after administration of PBS (the control) and sPDMA@ICG NPs. In these experiments, the laser irradiation (808 nm, 2 W/cm2, 5 min) was carried out locally at the periodontitis site. **indicates p < 0.01 compared to the control ( +); ##indicates p < 0.01 for comparison between two groups

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