Fig. 8

Effects of different vaccines on memory T cell responses, CTL response, and antibody levels. a Effector memory (CD44^hi CD62L^low) CD4⁺ T cells, b Cells of effector memory (CD44^hi CD62L^low) CD8⁺ T cells, c Central memory (CD44^hi CD62L^hi) CD4⁺ T cells, and D Central memory (CD44^hi CD62L^hi) CD8⁺ T cells. The expression of Perforin (e), CD107 (f), and FasL (g) on CD8⁺ T cell in splenocytes. h Anti-OVA IgG titers in the serum from mice after being immunized with different vaccines for 35 days. i The composition ratio of IgG1 and IgG2c in serum from mice after immunized with different vaccines for 35 days. Data were analyzed by flow cytometry and expressed as Mean ± STD (n = 6). (*p < 0.05; **p < 0.01; ***p < 0.001)