Fig. 2From: Engineered CRISPR-Cas systems for the detection and control of antibiotic-resistant infectionsCRISPR-Cas systems as antimicrobials. The Cas9 RNA-guided nuclease is expressed together with guide RNA that will direct it to cut a target sequence. The target can be carried on a plasmid or/and the chromosome, leading to resensitization to antibiotics or cell death due to chromosome degradation. (Created with BioRender.com)Back to article page