Skip to main content
Fig. 4 | Journal of Nanobiotechnology

Fig. 4

From: Quantifying intracellular trafficking of silica-coated magnetic nanoparticles in live single cells by site-specific direct stochastic optical reconstruction microscopy

Fig. 4

Micronuclei formation in MNPs@SiO2(RITC)-treated cells. Optical and fluorescence microscopic appearance of MNPs@SiO2(RITC)-treated a HEK293, b NIH3T3, and c RAW 264.7 cells. Here, red and blue indicate MNPs@SiO2(RITC) and Hoechst 33342, respectively. The scale bars in the lower-right corners are 20 μm. The yellow arrows indicate the micronuclei in each cell. d The frequencies of micronuclei-containing cells. More than 200 cells per experimental group were counted using ImageJ. Micronuclei were not detected in NIH3T3 (Green). Data represent mean ± S.D. related to the control of three independent experiments. *p < 0.05 in one-way ANOVA compared to each control group was considered significantly different

Back to article page