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Fig. 5 | Journal of Nanobiotechnology

Fig. 5

From: Augmented EPR effect post IRFA to enhance the therapeutic efficacy of arsenic loaded ZIF-8 nanoparticles on residual HCC progression

Fig. 5

Augmented enrichment of ICG@ZIF-8 NPs in residual tumors after IRFA. A UV–vis absorption absorbance spectra of ZIF-8 NPs, free ICG, and ICG@ZIF-8 NPs. B In vivo fluorescence imaging of ICG@ZIF-8 NPs in tumor-bearing nude mice. C, D Fluorescence imaging of dissected organs and tumors (D) and the related quantitative analysis chart (n = 4) (C). E, F In vivo enrichment of ICG@ZIF-8 NPs in tumors with or without IRFA (F) and the related quantitative analysis chart (n = 3) (E). R, IRFA. L, sham RFA (**P < 0.01)

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