Fig. 2From: A radioenhancing nanoparticle mediated immunoradiation improves survival and generates long-term antitumor immune memory in an anti-PD1-resistant murine lung cancer modelNanoString analysis of immune-gene expression in the secondary tumors. A Heatmap of the activities of various immune pathways. B Changes in gene expression in innate pathway, adaptive pathway, T cell and NK cell function in the NBTXR3 + HDXRT + LDXRT + ICIs group relative to the NBTXR3 + HDXRT + ICIs group and the HDXRT + LDXRT + ICIs group. C Relative scores for total tumor-infiltrating lymphocytes (TILs), dendritic cells, CD8 T cells, and regulatory T (Treg) cells. Data are expressed as means ± standard error of the mean (SEM). P < 0.05 was considered statistically significant. *P < 0.05, **P < 0.01, ***P < 0.001, NS not significant. HDXRT high-dose radiotherapy; LDXRT low-dose radiotherapy; ICIs immune checkpoint inhibitorsBack to article page