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Fig. 3 | Journal of Nanobiotechnology

Fig. 3

From: A radioenhancing nanoparticle mediated immunoradiation improves survival and generates long-term antitumor immune memory in an anti-PD1-resistant murine lung cancer model

Fig. 3

Flow cytometry analysis of CD4+ T cells, CD8+ T cells, and regulatory T cells (Tregs, labeled with CD4+FoxP3+) in the secondary tumors, harvested on day 16. A CD4+ T cell/CD45+ cell ratio. B CD8+ T cell/CD45+ cell ratio. C Treg CD4+FoxP3+ cell/CD45+ cell ratio. D CD8+ T cell/Treg CD4+FoxP3+ cell ratio. E Density of CD4+ T cells. F Density of CD8+ T cells. G Density of Treg CD4+FoxP3+ cells. Data are expressed as means  ±  standard error of the mean (SEM). P  < 0.05 was considered statistically significant. *P  < 0.05, **P  < 0.01, ***P  < 0.001, ****P  < 0.0001, NS not significant. HDXRT high-dose radiotherapy; LDXRT low-dose radiotherapy; ICIs immune checkpoint inhibitors

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