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Fig. 5 | Journal of Nanobiotechnology

Fig. 5

From: Biodegradable reduce expenditure bioreactor for augmented sonodynamic therapy via regulating tumor hypoxia and inducing pro-death autophagy

Fig. 5

In vivo biodistribution of the HHBP and the alleviation of hypoxia. a In vivo fluorescence image of 4T1 tumor-bearing mice at different time points after intravenous injection of ICG-loaded HHBP. The red arrows indicate the tumor sites. b HIF-1α staining tumor tissues harvested from 4T1 tumor-bearing mice after different treatments. c Fluorescence images of tumor slices were collected at 24 h after different treatments and staining with the ROS probe, dihydroethidium (DHE, red)

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