Fig. 5From: Biodegradable reduce expenditure bioreactor for augmented sonodynamic therapy via regulating tumor hypoxia and inducing pro-death autophagyIn vivo biodistribution of the HHBP and the alleviation of hypoxia. a In vivo fluorescence image of 4T1 tumor-bearing mice at different time points after intravenous injection of ICG-loaded HHBP. The red arrows indicate the tumor sites. b HIF-1α staining tumor tissues harvested from 4T1 tumor-bearing mice after different treatments. c Fluorescence images of tumor slices were collected at 24 h after different treatments and staining with the ROS probe, dihydroethidium (DHE, red)Back to article page