Fig. 7
Immunogenic CDT induced an immune-active TME in vivo. a Immunofluorescence staining of intratumor infiltrating CD8+ T cells after treatments with PBS, LOX, PLNP and PLNPCu. Scale bars, 100 μm. b The flow cytometry analysis of tumor infiltration of CD3+CD8+ T cells. c, d The flow cytometry analysis of ROS generation after treatments. e Immunofluorescence staining of intratumor ROS generation. Scale bars, 100 μm. Results were expressed as mean ± SD. The significant difference was calculated via one-way ANOVA analysis (b, c). (NS represented not significant, *p < 0.05, **p < 0.01, ***p < 0.001)