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Fig. 6 | Journal of Nanobiotechnology

Fig. 6

From: Regulating the production and biological function of small extracellular vesicles: current strategies, applications and prospects

Fig. 6

Modulated sEVs for cancer treatment [28, 97]. a, b Intra-tumor injection of exosomes derived from miR-146-expressing MSCs reduced 9L glioma growth in rat brain. All images are reproduced with permission from Katakowski et al. [28]. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved. c–e mRNA-containing exosomes produced by CNP enhanced inhibition of tumor growth and increased survival in orthotopic PTEN-deficient glioma mouse models. Exosome: normal, Exo-T: treated by CNP and contain PTEN mRNA, E-Exo-T: treated by CNP and empty with PTEN mRNA, Turbo: TurboFect nanoparticles. All images are reproduced with permission from Yang et al. [97]. Copyright © 2019 Author(s). All rights reserved

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