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Fig. 8 | Journal of Nanobiotechnology

Fig. 8

From: Irinotecan/scFv co-loaded liposomes coaction on tumor cells and CAFs for enhanced colorectal cancer therapy

Fig. 8

In vivo antitumor effect of subcutaneous inoculation of co-culture cells in mouse model. a Tumor volume of mice in each treatment group changed. b Tumor growth-inhibition rate. c Excised tumor photographs. d Body weight change during treatment. e H&E staining and f Ki67 immunohistochemistry (arrow indicates positive proliferation), TUNEL staining (brown indicates apoptosis) of tumor tissue. Scale bar, 50 μm. Significance criteria: *P < 0.05, **P < 0.01

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