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Fig. 4 | Journal of Nanobiotechnology

Fig. 4

From: Homologous targeting nanoparticles for enhanced PDT against osteosarcoma HOS cells and the related molecular mechanisms

Fig. 4

FL imaging of the different NPs in vivo. A, B FL images of HOS tumor-bearing mice and quantitative FL signal intensities within tumor regions before and after intravenous injection of different NPs at prolonged time points. C Ex vivo FL imaging of the tumor and major organs harvested from mice at 6 h post injection. D Semiquantitative biodistribution of tumors and major organs ex vivo was measured by the average FL intensities. (The data are presented as the mean ± SD values, n = 3, *p < 0.05). Biodistribution of MH-PLGA-IR780 NPs after intravenous injection in different tumor-bearing mice. E, F FL images and quantitative FL signal intensities of tumor regions at corresponding time points in vivo. (The data are presented as the mean ± SD values, n = 3, *p < 0.05). G, H Ex vivo FL images and semiquantitative analysis of major organs and tumors harvested from mice 6 h post-injection of MH-PLGA-IR780 NPs. (The data are presented as the mean ± SD values, n = 3, *p < 0.05)

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