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Fig. 8 | Journal of Nanobiotechnology

Fig. 8

From: Homologous targeting nanoparticles for enhanced PDT against osteosarcoma HOS cells and the related molecular mechanisms

Fig. 8

The specific mechanism of the induction of ferroptosis by targeted PDT. A The expression levels of ferroptosis-related proteins after different treatments detected by western blot. B Enhanced intracellular Fe2+ production of targeted PDT in HOS cells. CLSM images (labelled with FerroOrange) and FC analysis of Fe2+ generation after different treatments. The scale bars are 100 µm. C Western blot analysis of the expression levels of ferritinophagy-related proteins (NCOA4, FTH and FTL) after various treatments. D IF images of NCOA4, FTH and FTL in HOS cells after different treatments. The scale bars represent 20 µm

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Journal of Nanobiotechnology

ISSN: 1477-3155

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