a Chemical structures of amino group modified pillar[5]arene (AP5), ferrocene dicarbaldehyde (FeE), and target molecule FA-Py. b The illustration of preparation and modification of pillar[5]arene-based supramolecular therapeutic nano-platform. c The targeted synergistic chemo-chemodynamic cancer therapy of the multifunctional FA-Py/SP/GOx/Dox NPs