From: Unconjugated PLGA nanoparticles attenuate temperature-dependent β-amyloid aggregation and protect neurons against toxicity: implications for Alzheimer’s disease pathology
α-helical content (%)
β-sheet content (%)
Aβ1–42 (27 °C)
2
39
Aβ1–42 (37 °C)
42
Aβ1–42 (40 °C)
2.1
46
Aβ1–42 + PLGA (27 °C)
24
32
Aβ1–42 + PLGA (37 °C)
20
36
Aβ1–42 + PLGA (40 °C)
18