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Fig. 6 | Journal of Nanobiotechnology

Fig. 6

From: Thermo/pH dual-responsive micelles based on the host–guest interaction between benzimidazole-terminated graft copolymer and β-cyclodextrin-functionalized star block copolymer for smart drug delivery

Fig. 6

a Cell viability of MCF-7 cells after treatment with different concentrations of the blank micelles (PHEMA-g- (PCL-BM: β-CD-star-PMAA-b-PNIPAM)). b Cell viability versus drug dose of the free doxorubicin (DOX), and the drug-loaded micelles against human breast cancer cells (MCF-7) after incubation for 48 h. Each value represents the mean value ± standard deviation (n = 3, *p < 0.05, ** p < 0.01, *** p < 0.001). c Morphological changes of the MCF-7 cancer cell line after treatment with various formulations for 48 h (blank micelles concentration = 200 μg/ml and free DOX & DOX-loaded micelles concentrations = 50 μg/ml).

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