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Fig. 3 | Journal of Nanobiotechnology

Fig. 3

From: All-in-one theranostic nano-platform based on polymer nanoparticles for BRET/FRET-initiated bioluminescence imaging and synergistically anti-inflammatory therapy for ulcerative colitis

Fig. 3

BRET-FRET progress was evaluated in vitro and in vivo. A The excitation and emission spectra of luminol, DiL, and DiD. B The fluorescence spectra of BA/Res@NP-PBP at different concentrations of DiL. C Fluorescence spectra of BA/Res@NP-PBP with different DiL and DiD proportions. D Fluorescence spectra of BA/Res@NP-PBP with different total concentration. E Images of DiL/DiD-loaded BA/Res@NP-PBP under a confocal microscope. F Histogram of bioluminescence intensity statistics under different excitation lights. G The changes of luminescence emission with the dose of luminol. H The changes of luminescence emission with the dose of DiL/DiD-loaded BA/Res@NP-PBP. I The changes of luminescence emission with the changes of the time point. J Bioluminescence images of mice from different treatment groups. K Histogram statistics of bioluminescence images. *p < 0.05, **p < 0.01, and ***p < 0.001

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Journal of Nanobiotechnology

ISSN: 1477-3155

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