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Fig. 5 | Journal of Nanobiotechnology

Fig. 5

From: All-in-one theranostic nano-platform based on polymer nanoparticles for BRET/FRET-initiated bioluminescence imaging and synergistically anti-inflammatory therapy for ulcerative colitis

Fig. 5

The anti-inflammatory effect of BA/Res@NP and synergistic effects of BA and Res. A mRNA expression levels of IL-1β, TNF-α (B), IL-12 (C), and IL-6 (D) in LPS-induced Raw 264.7 cells were quantified by qRT-PCR (n = 5). E Cell apoptosis was detected by flow cytometry in Control, LPS, LPS + BA@NP, LPS + Res@NP, and LPS + BA/Res@NP group, respectively. In vitro cytotoxicity of NPs in Colon-26 cells. G In vitro cytotoxicity of NPs in Raw 264.7 cells. H CI-Fa plot. I Isobologram. *p < 0.05, **p < 0.005, ***p < 0.001

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