Fig. 4

A Fluorescence kinetics curves of the nanomachine with addition of 10 U Nt.BsmAI and target BCR/ABL fusion gene at different concentrations (from a to d: 2 μM, 2 nM, 2 pM and blank, separately). B The relationship between the slope of tangent at t = 0 s and logarithmic value of target BCR/ABL fusion gene concentrations (range of concentration: 2 pM, 2 nM, and 2 uM separately). C Time optimization of intermediate DNAs hybridizing with the capture DNA