Fig. 5
From: Engineered extracellular vesicles: potentials in cancer combination therapy
Engineered EVs for combinational chemo-photothermal therapy. Engineered EVs can co-delivery chemotherapeutic drugs and photothermal agents (PTAs) to tumor sites. Under near-infrared (NIR) irradiation, PTAs convert optical energy into heat for photothermal therapy (PTT). The elevated temperature can induce the collapse of the structure of engineered EVs and the controllable release of chemotherapeutic drugs to realize chemotherapy. Chemotherapy combined with PTT induces cancer cell death