Fig. 6
From: Engineered extracellular vesicles: potentials in cancer combination therapy
Engineered EVs for the combination of immunotherapy with chemotherapy. Immunomodulatory materials and chemotherapeutic drugs are co-delivered to the tumor microenvironment by engineered EVs. Immunomodulatory materials reprogram immunosuppressive cells to immune effector cells. Chemotherapy can induce immunogenic cell death (ICD) and expose more tumor antigens, facilitating better immunotherapy