Fig. 7
From: Quantitative hypoxia mapping using a self-calibrated activatable nanoprobe
Imaging of tumors with naturally developed hypoxia. a Representative fluorescence and fluorescence ratio images of tumors with different sizes, left tumor: 7.5 mm, right tumor: 4 mm. b Digital photo and IF images of the tumors in a; green: anti-HIF-1 \(\alpha\) staining, blue: DAPI, scale bar: 2 mm. c Scatter plot and correlation between HIF-1 \(\alpha\) expression and in vivo I800/I680 ratio, simple linear regression, p = 0.0041, R2 = 0.7717, n = 8