Fig. 3From: Young fibroblast-derived exosomal microRNA-125b transfers beneficial effects on aged cutaneous wound healingMiR-125b is involved in exosomeYoung -mediated wound healing.A Heat map of miRs differentially expressed in exosomeOld and exosomeYoung. B MiR-125b expression was validated by qRT-PCR in exosomeOld and exosomeYoung. *P < 0.05 versus exosomeOld in paired t-test (n = 6). C MiR-125b expression was validated by qRT-PCR after transfection of miR-125 mimic, or miR mimic negative control (NC) intradermally into the wound-edges. D Representative images of wound closure after local transfection of miR-125 mimic, or miR-NC mimic. E Relative wound area was calculated. *P < 0.05 versus miR-125b mimic in one-way analysis of variance (n = 6)Back to article page