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Fig. 2 | Journal of Nanobiotechnology

Fig. 2

From: Doxorubicin and CpG loaded liposomal spherical nucleic acid for enhanced Cancer treatment

Fig. 2

A Cell viability of HUVEC after incubation with various concentrations of hNPs or free DOX and CpG. B Quantification of the cellular uptake of DOX by E.G7-OVA cells. C Representative CLSM images of E.G7-OVA cells after incubation with DOPE-DOX NPs or free DOX for 2 h, 4 h and 6 h, respectively. The molecule expression of D CD40 and E MHC-II was analyzed by flow cytometry. The cytokine expression of F TNF-α, G IFN-γ and H IL-1β were analyzed by ELISA assays. Results represent mean ± SD (n = 6; *P < 0.05, **P < 0.01, ***P < 0.001)

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