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Fig. 1 | Journal of Nanobiotechnology

Fig. 1

From: Microparticles: biogenesis, characteristics and intervention therapy for cancers in preclinical and clinical research

Fig. 1

Biosynthesis and physiological functions of microparticles (MPs). Ca2+, released from the endoplasmic reticulum, regulates the activity of flippase, floppases and scramblases to translocate phosphatidylserine to the outer cell surface, modulating the asymmetry of membrane lipids and increasing curvature of the local membrane. Followed by actomyosin contraction, the outward budding of the membrane splits and MPs are released from the cell surface

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