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Table 1 Comparisons of EVs

From: Microparticles: biogenesis, characteristics and intervention therapy for cancers in preclinical and clinical research

Characteristic EXOs MPs Apoptotic bodies
Origin Multivesicular bodies Plasma membrane Plasma membrane
Size 30–100 nm 100–1000 nm 1000–5000 nm
Density 1.13–1.19 g/cm3 1.04–1.07 g/cm3 1.16–1.28 g/cm3
Sedimentation  ≥ 100000 g 10000–20000 g 2000 g and various
Zeta potential − 16.35 ~ − 11.85 mV − 30 ~ − 10 mV /
Appearance Cup-shaped Irregular-shaped Irregular-shaped
Markers TSG101, tetraspanins and Alix Integrins, selectins and CD40 ligand Histones, Annexin V