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Fig. 9 | Journal of Nanobiotechnology

Fig. 9

From: Biomimetic GBM-targeted drug delivery system boosting ferroptosis for immunotherapy of orthotopic drug-resistant GBM

Fig. 9

Effect of Fe3O4-siPD-L1@M-BV2 on polarization of microglia in orthotopic drug-resistant GBM tissue. A Distribution of microglia (marked with Iba-1, red color) in orthotopic drug-resistant GBM tissue. T: tumor tissue; N: normal tissue. B M1-type microglia (Iba-1 and CD16/32 co-positive cells) and M2-type microglia (Iba-1 and CD206 co-positive cells) in orthotopic drug-resistant GBM tissue. C, D Statistic analysis of M1 type and M2 type microglia in orthotopic drug-resistant GBM tissue. (n = 3, mean ± SD, *P < 0.05, **P < 0.01)

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