Table 4 List of NCs used in clinics or in clinical trials [200]
From: Nanocarrier cancer therapeutics with functional stimuli-responsive mechanisms
Products | Drug | Nanocarrier | Application |
|---|---|---|---|
In clinics | |||
 ADI-PEG 20 | Arginine deaminase | Polymeric | Hepatocellular carcinoma |
 Doxil | Doxorubicin | Polymeric | Leukemia, lymphoma, and carcinoma |
 AP5280 | Platinum | Polymeric | Solid tumors |
 DepoCyt | Cytarabine | Liposomal | Lymphomatous meningitis |
 MAG-CPT | Camptothecin | Polymeric | Solid tumors |
 Visudyne | Verteporfin | Liposomal | Macular degeneration |
 Oncaspar | L-Asparaginase | Polymeric | Lymphoblastic leukemia |
 Pegasys | Interferon alfa-2a | Polymeric | Hepatitis B and hepatitis C |
Clinical trials | |||
 PNU166945 | Paclitaxel | Polymeric | Solid tumors |
 Lipoplatin | Cisplatin | Liposomal | Non-small cell lung cancer |
 XMT-1001 | Camptothecin | Polymeric | Gastric cancer and lung cancer |
 Onco-TCS | Vincristine | Liposomal | Relapsed non-Hodgkin lymphoma |
 OSI-211 | Lurotecan | Liposomal | Head, neck, and ovarian cancer |
 SPI-077 | Cisplatin | Liposomal | Head, lung, and neck cancer |
 PEG-SN38 | Irinotecan derivate | Polymeric | Solid tumors and breast cancer |
 Livatag | Doxorubicin | Polymeric | Liver cancer |
 NKTR-105 | Docetaxel | Polymeric | Solid tumors and ovarian cancer |
 Paclical | Paclitaxel | Polymeric | Breast, lung, and ovarian cancer |
 PEG-docetaxel | Docetaxel | Polymeric | Solid tumors |