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Fig. 3 | Journal of Nanobiotechnology

Fig. 3

From: Identification and evaluation of circulating small extracellular vesicle microRNAs as diagnostic biomarkers for patients with indeterminate pulmonary nodules

Fig. 3

Classifier development process for IPNs. a Heatmap of sEV-miRNA expression in the training cohort by unsupervised hierarchical clustering. b Expression levels of six identified DEMs in the training cohort. c ROCs of classifiers constructed with different combinations of the six DEMs. Only ROCs with the best diagnostic powers of different miRNA combinations are shown. d ROC curve of the CirsEV-miR model in the training cohort. e CirsEV-miR scores of benign and malignant PNs in the training cohort

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