Fig. 6

AIS/MIA are intermediate between benign and malignant PNs. a The CirsEV-miR scores of the benign, AIS/MIA, and invasive adenocarcinoma subgroups categorized according to the pathologies. b Gene expression heatmap of all genes in the benign, AIS/MIA and invasive adenocarcinoma subgroups. c The expression levels of the five DEMs in the benign, AIS/MIA, and invasive adenocarcinoma subgroups. d, e Venn diagrams of upregulated (d) or downregulated (e) genes of the benign, AIS/MIA, and IA subgroups. f Overall survival analysis of miR-30c-5p, miR-30e-5p, miR-500a-3p, miR-125a-5p, and miR-99a-5p from the TCGA database. ***, p < 0.001; **, p < 0.01; *, p < 0.05; ns, not significant