Fig. 6
From: Bacteria-driven hypoxia targeting delivery of chemotherapeutic drug proving outcome of breast cancer
Anti-tumor activity of Bif@DOX-NPs against 4T1 tumors in mice. Tumor growth curves (D), body weight curves (E) and survival curves (F) of mice receiving different therapeutic regimens as shown in panel A (n = 6, **P < 0.01, ****P < 0.0001). B Representative photos of 4T1 tumor-bearing mice on the 14th day after various treatments. a: Control, b: Bif, c: Bif@BSA-NPs, d: DOX + Bif, e: DOX-NPs, f: Bif@DOX-NPs. C Representative photographs of isolated tumors. a to f means the same group as above. G The tumor volume of mice during different treatments at 14 d. H In vivo drug concentration distribution. Results are expressed as mean ± SD (n = 3, ***P < 0.001, ****P < 0.0001)