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Fig. 4 | Journal of Nanobiotechnology

Fig. 4

From: Multifunctional nanoparticles co-loaded with Adriamycin and MDR-targeting siRNAs for treatment of chemotherapy-resistant esophageal cancer

Fig. 4

modified by Cy3. D A laser confocal microscope detected the uptake of CEAMB NPs. DAPI is blue (excitation wavelength 364 nm), and Adriamycin is green (excitation wavelength 488 nm), and SiRNA is red (excitation wavelength 532 nm). Scale bar, 20 µm

The detection of targeted adhesion and cellular uptake of CEAMB NPs in 510K cells. A Cells were incubated with different reagents, including blank, siRNA, CAMB NPs, CEAMB NPs, and cell adhesion was detected using Flow cytometry. Cy3-siRNA (excitation wavelength 532 nm), Adriamycin (excitation wavelength 488 nm). B The tumor cell adhesion efficiency of different reagents. *p < 0.05, **p < 0.01, double-tailed t-test. C Flow cytometry detected the uptake of CEAMB NPs. siRNA was

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