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Fig. 1 | Journal of Nanobiotechnology

Fig. 1

From: Extracellular vesicle-mediated crosstalk between pancreatic cancer and stromal cells in the tumor microenvironment

Fig. 1

Multiple roles of pancreatic ductal adenocarcinoma (PDAC)-derived extracellular vesicles (EVs) in altering the phenotypes of recipient stromal cells in the tumor microenvironment (TME) and shaping a pathologically active environment favoring tumor progression. Cancer cells and stromal cells both utilize EVs to influence surrounding cells within the TME niche by transferring bioactive molecules, including microRNAs

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