Fig. 5From: Multistage pH-responsive codelivery liposomal platform for synergistic cancer therapyGene silencing efficacy and cytotoxicity evaluation. a Expression of the PLK-1 mRNA determined using qRT–PCR. b Expression of the PLK-1 protein determined using western blot analysis. Cell apoptosis following exposure to (c) liposomes carrying individual drugs and (d) codelivery liposomes. Early apoptotic cells are shown in the lower right quadrant, and late apoptotic cells are shown in the upper right quadrant. *P < 0.05 and **P < 0.01Back to article page