Table 1 Physicochemical properties of liposomes carrying siRNA or siRNA/DTX (n = 3)
From: Multistage pH-responsive codelivery liposomal platform for synergistic cancer therapy
| Â | Functional arms [mol ratio of total lipid] | Diameter [nm] | PDI | Zeta-potential [mV] |
|---|---|---|---|---|
N-LR/si | – | 184.5 ± 2.3 | 0.098 ± 0.012 | − 38.8 ± 0.78 |
C-LR/si | DSPE-PEG2000-CPP [5%] | 191.6 ± 3.7 | 0.133 ± 0.016 | − 28.4 ± 1.24 |
D-LR/si | DSPE-PEG2000-DPRP [5%] | 202.9 ± 1.7 | 0.187 ± 0.023 | − 34.3 ± 1.21 |
D-LH/si | DSPE-PEG2000-DPRP [5%] | 209.9 ± 0.6 | 0.194 ± 0.021 | − 36.4 ± 2.20 |
D-LH/si-DTX | DSPE-PEG2000-DPRP [5%] | 211.3 ± 1.6 | 0.219 ± 0.012 | − 36.1 ± 1.46 |