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Fig. 3 | Journal of Nanobiotechnology

Fig. 3

From: Double-activation of mitochondrial permeability transition pore opening via calcium overload and reactive oxygen species for cancer therapy

Fig. 3

a The images of 4T1 cells incubated with FCCF recorded at different time points. b [Ru(dpp)3]Cl2 was used as probe to detect O2 generation after treatment with: (1) PBS + , (2) FCCF, (3) FCCF + and (4) OFCCF + . c Western blot analysis of HIF-1α expression of 4T1 cells. d Mitochondrial distribution and mitochondrial membrane potential images of 4T1 cells after different treatments. e Bio-TEM images of 4T1 cells after different treatments. Red arrows exhibit the location of destructed mitochondria in 4T1 cells

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Journal of Nanobiotechnology

ISSN: 1477-3155

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